Sheikh Mohammad Fazle Akbar Selected Research

Hepatitis B Core Antigens

12/2021	The Safety and Efficacy of a Therapeutic Vaccine for Chronic Hepatitis B: A Follow-Up Study of Phase III Clinical Trial.
11/2021	Sustained Antiviral and Liver Protection by a Nasal Therapeutic Vaccine (NASVAC, Containing Both HBsAg and HBcAg) in Patients with Chronic Hepatitis B: 2-Year Follow-Up of Phase III Clinical Trial.
1/2018	Treatment of chronic hepatitis B naïve patients with a therapeutic vaccine containing HBs and HBc antigens (a randomized, open and treatment controlled phase III clinical trial).
10/2013	Therapeutic potential of a combined hepatitis B virus surface and core antigen vaccine in patients with chronic hepatitis B.
8/2013	HBsAg, HBcAg, and combined HBsAg/HBcAg-based therapeutic vaccines in treating chronic hepatitis B virus infection.
10/2012	Strong and multi-antigen specific immunity by hepatitis B core antigen (HBcAg)-based vaccines in a murine model of chronic hepatitis B: HBcAg is a candidate for a therapeutic vaccine against hepatitis B virus.
8/2010	Impaired dendritic cell functions disrupt antigen-specific adaptive immune responses in mice with nonalcoholic fatty liver disease.

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Sheikh Mohammad Fazle Akbar Research Topics

Disease

16	Chronic Hepatitis B 05/2022 - 01/2010
7	Hepatitis B 06/2021 - 06/2011
7	Infections 01/2020 - 01/2010
4	Hepatocellular Carcinoma (Hepatoma) 01/2019 - 07/2012
3	COVID-19 04/2021 - 12/2020
3	Liver Diseases (Liver Disease) 01/2020 - 06/2010
2	Fibrosis (Cirrhosis) 12/2021 - 01/2012
2	Acute-On-Chronic Liver Failure 06/2021 - 11/2017
2	Liver Cirrhosis (Hepatic Cirrhosis) 01/2019 - 06/2011
2	Non-alcoholic Fatty Liver Disease 01/2016 - 08/2010
2	Neoplasms (Cancer) 06/2014 - 01/2013
2	Chronic Hepatitis (Chronic Active Hepatitis) 01/2013 - 06/2010
2	Inflammation (Inflammations) 01/2012 - 06/2011
1	Coronavirus Infections 01/2022
1	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2018
1	Neuroinflammatory Diseases 01/2018
1	Alzheimer Disease (Alzheimer's Disease) 01/2018
1	Hepatitis C 11/2017
1	Hyponatremia 11/2017
1	Hepatorenal Syndrome 11/2017
1	Renal Insufficiency (Renal Failure) 11/2017
1	End Stage Liver Disease 11/2017
1	Cysts 01/2015
1	Obesity 01/2015
1	Neoplasm Metastasis (Metastasis) 06/2014
1	Urinary Bladder Neoplasms (Bladder Cancer) 06/2014
1	Melanoma (Melanoma, Malignant) 01/2013
1	Liver Neoplasms (Liver Cancer) 01/2013

Drug/Important Bio-Agent (IBA)

11	Hepatitis B Surface Antigens (HBsAg)FDA Link 12/2021 - 01/2010
9	AntigensIBA 01/2020 - 01/2010
8	VaccinesIBA 12/2021 - 01/2010
8	Antiviral Agents (Antivirals)IBA 11/2021 - 01/2010
7	Hepatitis B Core AntigensIBA 12/2021 - 08/2010
7	DNA (Deoxyribonucleic Acid)IBA 12/2021 - 01/2012
4	Hepatitis B e AntigensIBA 01/2020 - 06/2011
4	Alanine Transaminase (SGPT)IBA 01/2020 - 01/2011
3	Ivermectin (Mectizan)FDA Link 04/2021 - 12/2020
3	CytokinesIBA 01/2020 - 08/2010
2	InterferonsIBA 01/2018 - 07/2012
2	Biomarkers (Surrogate Marker)IBA 01/2013 - 06/2011
2	Hepatitis B Vaccines (Hepatitis B Vaccine)IBA 08/2010 - 06/2010
1	Pharmaceutical PreparationsIBA 12/2021
1	Telbivudine FDA Link 06/2021
1	Tenofovir (Viread)FDA Link 06/2021
1	gamma- hydroxy- gamma- ethyl- gamma- phenylbutyramide (HEPB)IBA 04/2021
1	N-acetyltalosaminuronic acid (NAT)IBA 01/2020
1	Nucleic AcidsIBA 01/2018
1	Amyloid (Amyloid Fibrils)IBA 01/2018
1	Immunoglobulin M (IgM)IBA 11/2017
1	Immunoglobulin G (IgG)IBA 11/2017
1	Cytidine Triphosphate (CTP)IBA 11/2017
1	Granulocyte Colony-Stimulating Factor (G-CSF)IBA 11/2017
1	Macrophage Colony-Stimulating FactorIBA 01/2016
1	CCR2 ReceptorsIBA 01/2016
1	Chemokine CCL2 (Monocyte Chemoattractant Protein 1)IBA 01/2016
1	Drinking WaterIBA 01/2015
1	Small Interfering RNA (siRNA)IBA 06/2014
1	Proteins (Proteins, Gene)FDA Link 06/2014
1	Therapeutic UsesIBA 08/2013
1	Fc Receptors (Fc Receptor)IBA 01/2013
1	Membrane Glycoproteins (Membrane Glycoprotein)IBA 01/2013
1	Immunoglobulins (Immunoglobulin)IBA 01/2013
1	DNA PrimersIBA 07/2012

Therapy/Procedure

9	Therapeutics 01/2020 - 06/2010
2	Investigational Therapies (Experimental Therapy) 05/2022 - 06/2011
2	Immunotherapy 01/2016 - 07/2013
1	Secondary Prevention 01/2022